Hydroxypropyl methyl cellulose HPMC he cellulose kore-katote i konatunatua ether i roto i te momo me te katote methyl carboxymethyl cellulose etere whakauru, e kore e tauhohe ki nga konganuku taumaha.Ko tetahi rauropi hāora na te mea o te hydroxypropyl methyl cellulose content me te rerekee o te ahua o te hydroxypropyl content and viscosity, he momo rereke i runga i te mahi, hei tauira, te nui o te methoxyl me te iti o nga momo hydroxypropyl, he tata ki te methyl cellulose me te methoxyl iti. te ihirangi me te nui o nga momo hydroxypropyl, a he tata ki te hydroxypropyl methyl cellulose kua puta.Engari i roto i ia momo, ahakoa he iti noa iho te hydroxypropyl, he iti noa ranei o te methoxy, ko te whakarewatanga i roto i nga whakarewa pararopi, te pāmahana flocculation ranei i roto i te wairewa wai, he rereketanga nui.
1, hydroxypropyl methyl cellulose memehatanga
Hydroxypropyl methyl cellulose i roto i te wai whakarewatanga o te hydroxypropyl methyl cellulose he tino momo propylene oxide (methyl oxypropyl ring) kua whakarereketia te methyl cellulose, na reira he rite tonu ki te methyl cellulose te wai matao wairewa me te wai wera nga ahuatanga koretake.Heoi ano, he nui ake te pawera o te hauwai o te propyl hydroxy whakarerekē i tera o te methyl cellulose i roto i te wai wera.Hei tauira, ko te viscosity o te wairewa wai hydroxypropyl methylcellulose me te 2% methoxy content DS=0.73 me te ihirangi hydroxypropyl MS=0.46 he 500 mpa i te 20 ℃.He tata ki te 100 ℃ te paemahana rā o te hua o S, i te mea ko te methyl cellulose he rite tonu te pāmahana he 55 ℃ noa iho.Ko tona memehatanga i roto i te wai, hoki tino pai ake, hei tauira, i muri i te kuru o te hydroxypropyl methylcellulose (te ahua witi 0.2 ~ 0.5mm i 20 ℃ 4% wai pokey o 2pA? Ka taea te ngāwari rewa S hua i roto i te wai, kahore tautauā i te pāmahana rūma. .
(2) Hydroxypropyl methyl cellulose i roto i te whakarewa pararopi te whakarewatanga o te hydroxypropyl methyl cellulose i roto i nga whakarewa pararopi, he pai ake i te methyl cellulose, me te methyl cellulose e hiahia ana i roto i te tohu whakakapi methoxy o te 2.1 neke atu ranei nga hua, kei roto te hydroxypropyl MS = 1.5 ~ 1.8 me te methoxy. DS=0.2~1.0, High viscosity hydroxypropyl methyl cellulose me te katoa o te tohu whakakapinga i runga ake i te 1.8 he wairewa i roto i te wairewa methanol anhydrous me te wairewa wairewa, a he whakamaarama me te wairewa wai.He wairewa ano i roto i te waiwaro maota penei i te dichloromethane me te trichloromethane, me nga whakarewa pararopi penei i te acetone, te waipiro isopropyl, me te waipiro diacetone.He pai ake te whakarewatanga o te wairewa i te wairewa.
2, hydroxypropyl methyl cellulose viscosity o nga mea whakaawe
Hydroxypropyl methylcellulose viscosity factors hydroxypropyl methylcellulose whakatau pokey paerewa, me etahi atu cellulose ether he rite, kei te 20 ℃ me te 2% wairewa wai hei whakatau paerewa.Ko te viscosity o te hua kotahi, me te piki ake o te kukū me te piki ake, ko te rite o te kukū o nga hua taumaha momo rereke, ko te taumaha ngota o te hua he nui te pokey.Ko tona hononga ki te pāmahana he rite ki te methyl cellulose.Ka piki ake te pāmahana, ka timata te heke o te pokey, engari ka tae ki tetahi pāmahana, ka piki ohorere te pokey, ka puta te wai.He teitei ake te paohana o nga hua ki te pokey iti i tera o nga hua ki te pokey teitei.Ko te taumata o tona ira gel, i tua atu i te teitei me te iti o te viscosity o te ether, engari me te ether methoxy me te hydroxypropyl group composition ratio me te katoa o te tohu whakakapi e hono ana.Me tohu ko te hydroxypropyl methylcellulose he pseudoplastic hoki;he pūmau tana otinga ka penapena ki te pāmahana rūma, ā, karekau e whakaatu he paheketanga o te pokey hāunga te tūponotanga o te whakakino enzymatic.
3, hydroxypropyl methyl cellulose waikawa me te ātete kawakore
Hydroxypropyl methylcellulose waikawa alkali hydroxypropyl methylcellulose waikawa me te alkali, te tikanga he pūmau, i roto i te ph PH2 ~ 12 awhe e kore e pā, ka taea e tu te reira i te nui etahi o te waikawa marama, pērā i te waikawa formic, waikawa acetic, waikawa citric, waikawa succinic, phosphoric te waikawa, te waikawa boric, me etahi atu. Engari ko te waikawa kukū te hua o te whakaheke i te pokey.Karekau he painga ki runga i te wai kawa penei i te houra, te pāhare pāporo me te kotakota, engari ko te hua o te whakanui paku te pokey o te otinga ka iti haere a muri ake nei.
4, ka taea te whakauru hydroxypropyl methyl cellulose
Ko te wairewa Hydroxypropyl methyl cellulose ka taea te konatunatua ki te wai-wairewa polymer pūhui, ka waiho hei otinga marama rite ki te pokey teitei.Ko enei pūhui ngota teitei ko te polyethylene glycol, te polyvinyl acetate, te polysilicone, te polymethyl vinyl siloxane me te hydroxyethyl cellulose me te methyl cellulose, me etahi atu. otinga.Hydroxypropyl methyl cellulose taea hoki te konatunatua ki te waikawa stearic waikawa palmitic waikawa mannitol hākawa sorbitol ranei, engari ano ki te glycerol, sorbitol me mannitol, Ka taea te whakamahi i enei pūhui rite hydroxypropyl methyl cellulose plasticizer.
5, hydroxypropyl methyl cellulose wairewa wairewa
Ko te Hydroxypropyl methyl cellulose te wai-wairewa cellulose etera, ka taea te hono-whakawhiti ki te mata me te aldehydes, me te hanga i enei eter wai-wairewa i roto i te wairewa, ka kore e rewa ki te wai.A ka hanga hydroxypropyl methylcellulose aldehyde, formaldehyde, glyoxal, succinaldehyde, dialdehyde, me etahi atu, ko te whakamahinga o te formaldehyde me aro nui ki te uara PH o te otinga, he tere ake te tauhohenga o te glyoxal, na i roto i nga mahi ahumahi e whakamahia ana te glyoxal hei ripeka. - kaihoko hono.Ko te inenga o tenei ahua o te kaihoko whakawhiti i roto i te otinga ko te 0.2% ~ 10% o te papatipu ether, ko te pai rawa atu ko te 7% ~ 10%, penei i te whakamahinga o te glyoxal me te 3.3% ~ 6% te tino tika.Ko te pāmahana maimoatanga whānui ko 0 ~ 30 ℃, te wa ko 1 ~ 120min.Me whakahaere te tauhohenga honohono i raro i nga tikanga waikawa.Ko te tikanga, ka taapirihia te waikawa kaha pararopi, te waikawa warowaikawa waro ranei ki te otinga hei whakatika i te PH o te otinga ki te 2~6, he pai ki waenga i te 4~6, katahi ka taapirihia nga aldehydes mo te tauhohenga honohono.Ko nga waikawa e whakamahia ana ko te waikawa waikawa, te waikawa sulfuric, te waikawa phosphoric, te waikawa formic, te waikawa acetic, te waikawa acetic hydroxy, te waikawa succinic, te waikawa citric ranei, i roto i enei ko te waikawa formic, waikawa acetic ranei te mea pai, ko te waikawa formic te mea pai.Ka taea hoki te taapiri i te waikawa me te aldehydes i te wa ano kia taea ai te hono te otinga ki te awhe PH e hiahiatia ana.He maha nga wa e whakamahia ana tenei tauhohenga i roto i te tukanga whakamutunga o te tukanga whakarite cellulose ether, kia kore ai e memeha te ether cellulose, ngawari ki te whakamahi i te wai 20 ~ 25 ℃ hei horoi me te purea.I te wa e whakamahia ana te hua, ka taea te taapiri i nga matū kawakore ki te otinga o te hua hei whakatika i te PH o te otinga kia kawakore, ka tere te rewa te hua i roto i te otinga.Ka taea hoki te whakamahi i tenei tikanga ina whakamahia te wairewa cellulose ether ki te hanga kiriata katahi ka tukuna te kiriata ki te hanga kiriata kore.
6, hydroxypropyl methyl cellulose anti-enzyme
Hydroxypropyl methyl cellulose whākōkī ātete o cellulose pärönaki i roto i te ariā, pērā i ia rōpū anhydroglucose pērā i te mea he huinga totoka o whakakapi rōpū, horo o microorganisms he iti whakaraerae ki te mate, engari i roto i te meka te hua oti ki te whakakapi i te uara neke atu i te 1, na te paheketanga o te whākōkī, koinei te whakaahuatanga o ia roopu i roto i te tohu whakakapi mekameka cellulose kaore i te rite, Ka taea e nga Microorganisms te whakakore tata ki nga roopu hukahuka kore i whakakapihia hei hanga huka, ka taea e nga microorganisms hei kai.No reira, ki te piki te tohu whakakapinga whakaeera o te cellulose, ka kaha ake te aukati o te cellulose ether ki te horo enzymatic.E ai ki te korero, i raro i nga tikanga whakahaere, ko te toenga o te kirikiri o te hydroxypropyl methyl cellulose (DS=1.9), te methyl cellulose (DS=1.83), te methyl cellulose (DS=1.66), me te hydroxyethyl cellulose (1.7%) he 13.2%, 7.3% , 3.8%, me te 1.7%.Hydroxypropyl methyl cellulose he kaha anti-enzyme kaha.Na hydroxypropyl methylcellulose anti-enzyme pai, ngā ki tona marara pai, thickening me te hanga kiriata, tono i roto i paninga whakaehunga, me ētahi atu, te tikanga e kore e hiahia ki te tāpiri i te korotutu.Heoi, hei aukati i te rokiroki mo te wa roa o te otinga, te poke ranei mai i te ao o waho, ka taea te taapiri i nga whakamarumaru, ka taea te whakatau i tana kowhiri i runga i nga whakaritenga whakamutunga o te otinga.Ko te Phenylmercuric acetate me te manganese fluosilicate he rongoa whai hua, engari he paitini, me ata whakahaere.Ko te tikanga, ka taea te taapiri 1~5mg acetate phenylmercuric ki ia rita o te otinga.
7, hydroxypropyl methyl cellulose membrane mahi
Hydroxypropyl methyl cellulose kiriata mahi o hydroxypropyl methyl cellulose he kiriata pai, tona wairewa wairewa wairewa wairewa wairewa ranei, pani ki runga ki te pereti karaihe, i muri i te whakamaroke ka kore tae, marama me te uaua kiriata.He pai te aukati makuku me te pumau tonu i nga wera teitei.Pērā i te tāpiritanga o te plasticizer hygroscopic, ka taea te whakarei ake i tona elongation me te ngāwari, ki te whakapai ake flexure, glycerol me sorbitol me ētahi atu plasticizer ko te tino tika.Ko te kukū otinga whānui ko 2% ~ 3%, te inenga plasticizer ko 10% ~ 20% o te cellulose ether.Mena kei te hiahia te ihirangi o te plasticizer, ka puta te ahua o te whakahekenga o te whakahekenga o te colloid i te haumākū nui.Ko te kaha tensile o te kiriata i tapirihia te plasticizer he nui ake i te mea kaore i taapiri, ka piki ake ki te piki ake o te nui o te taapiri, na te mea ko te hygroscopicity o te kiriata ka piki ake me te piki o te nui o te plasticizer.
Te wa tuku: Sep-08-2022